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4th MURI/AFOSR Workshop

Advances in biostimulation with nanosecond pulsed electric fields.

Co-Chairs: Andrei Pakhomov, Yasir Alfadhl

Scope: We will present and discuss latest research on molecular and cellular mechanisms underlying bioeffects of nanosecond pulsed electric fields (nsPEF). Topics include electropermeabilization and membrane repair; pore opening, life cycle, and conductive properties; response of ion channels; activation of signaling cascades and diverse cell functions.

Particular attention will be given to the phenomenon of bipolar cancellation (the inhibition of nsPEF bioeffects upon the reversal of the electric field polarity) and its applications for stimulation and tissue ablation at a distance. The Workshop welcomes all BioEM2020 participants. No additional registration is needed.

Electromagnetic fields mediated detection and neutralization of cancer stem cells: the SUMCASTEC approach

Chair: Caterina Merla

Scope: The Workshop aims to present results concerning new EM-based diagnostic and therapeutic approaches targeting cancer stem cells (CSCs). The main aim is to achieve the fast detection and manipulation CSCs as they represent a particular subpopulation of tumoral cells expressing a quiescent state and high self-renewal potential. These peculiar characteristics make them able to escape current cancer treatments and to regenerate tumors, leading to frequent relapses of the pathology.

EMFs are applied on one side to discriminate CSCs from cancer cells and on the other side to attempt to affect, in a controlled fashion, their functions. Results concerning the fast isolation of CSCs mediated by radio frequency fields in a lab on chip platform integrating CMOS technology and microfluidics will be discussed. The workshop will cover also bio-effects (in vitro and in vivo) induced by different types of pulsed electric fields on brain tumor CSCs. This workshop proposes a complete view of the use EMFs in diagnosis and therapy disclosing innovative potentials for a range a novel bio-medical applications targeting CSCs. No additional registration is needed.

Risk assessment of localized exposure - theory and hands-on

Chair: Peter Jeschke

Scope: The workshop aims to provide a thorough insight into the theory, dosimetry, and assessment of local exposures in occupational EMF settings. Up until a few years ago, localized exposure was of interest only to the domain of occupational EMF exposure. Only recently, with innovations around smartphones and smart body worn devices localized exposures are becoming a matter of interest to the general public as well.

To begin with, theory presentations will cover the background of near-field physics, possible health effects in LF and HF near-field EMF, typical exposure settings, and an introduction of international guidelines, i.e. IEEE or ICNIRP. The hands-on part will provide participants with an insight into measurement of selected LF- and RF-EMF sources. No additional registration is needed.

Systematic review of EMF health hazard research: Strengths and limitations of methods developed for clinical trial evidence synthesis

Chair: Susanna Lagorio

Scope: Systematic reviews have the potential to increase transparency, reduce the risk of bias, and improve the reliability of the evidence assessment. A common language to grade the weight (or certainty) of evidence can facilitate risk communication. These advantages underlie the risk assessment methods used by WHO and the European Commission’s scientific committees.

The synthesis and appraisal of the scientific evidence on health hazards from radiofrequency electromagnetic fields, however, is hampered by some criticalities. The wide range of outcomes or endpoints investigated in relation to low-level exposures, with no clear biological hypotheses, is a problem common to all relevant research lines. Additional challenges with the systematic review approach will be illustrated separately for three streams of evidence: observational epidemiologic studies, experimental studies on animal models, and experimental studies on isolated biological systems. No additional registration is needed.

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Oxford BIOEM 2020
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The Old Bank

The independently owned Old Bank, centrally located on Oxford’s famous High Street, is a breath-taking statement in design. Situated in the heart of historical Oxford, The Old Bank offers rooms which feature marble bathrooms and modern art. Oxford University is located just 300m from the property. Free Wi-Fi is available throughout the hotel. The spacious rooms are air conditioned and elegantly decorated. Rooms also offer a TV and plenty of work space. Many have original period features and views across the city. Guests can enjoy breakfast, lunch, afternoon tea or dinner in Quod restaurant with its terrace and bar. Traditional roast dinners are available. The hotel has meeting rooms and private dining rooms. Room service is also available. Just steps away from Merton, All Souls and Oriel Colleges, The Old Bank is a five-minute walk from the Botanic Garden. Magdalen Bridge and the River Cherwell can also be reached in five minutes, and Oxford Train Station is a 15-minute walk away.

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The Principal Oxford Spires

Within easy walking distance of Oxford's colleges, museums and theatres, this is the perfect base from which to discover everything that one of the most historic cities in England has to offer. After the hustle and bustle of the city, we are the perfect antidote. When you walk through the doors you’ll feel yourself sigh with relief as you delight in our relaxed and contemporary feel. A sanctuary of calm just moments from the throng. Whilst you’re here, take time to enjoy the tranquillity of the River Thames – just one minute away – and take a stroll around our apple orchard and gardens. If you’re lucky (and quiet) you might even spot our resident family of muntjac deer. No matter what brings you to our door, whether it be a work trip or a weekend away, we are here to play host and make sure you have everything you need. It’s time to eat, sleep and everything in between.

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Old Parsonage Hotel

Oxford’s 17th century Old Parsonage combines original charm and character with all the luxury, amenities and technology available to an independently owned 5-star hotel. Best known by locals and visitors alike for its eclectic country house charm, chic modern interiors and striking 20th century portraits, the Old Parsonage is a luxury home-from-home with impeccable hospitality. A striking balance of old & new, each of the 35 individually designed bedrooms & suites feature luxurious handmade beds, rich natural fabrics, unique Oxford sketches and magnificent marble bathrooms. Guests can enjoy afternoon tea in the walled courtyard, relax within the peaceful & stunning surrounds of a carefully curated library, or explore the city the traditional way and borrow one of the hotel's vintage style bicycles. The Parsonage Grill, famous for its intimate, bohemian, clubby atmosphere, displays an amazing collection of eclectic oil paintings; mainly portraits of well-known writers and artists. The state-of-the-art kitchen uses the best local produce to create classic, simple yet innovate British dishes. Open every day of the year, enjoy breakfast, lunch, dinner and our famous afternoon teas, in the company of Oxford’s academic and literary luminaries. The exclusive residents’ library is the perfect space in which to relax, read and enjoy a drink or a bite to eat. A carefully curated collection of books will inspire & entertain, and includes a section on art, literature, culture & politics, Oxford & its history. Relax amongst a specially commissioned collection of Paddy Summerfield’s black and white photographs of 1960’s Oxford.

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Vanbrugh House Boutique Hotel

Small and intimate, yet intensely stylish and luxurious, the Vanbrugh House Oxford Hotel boasts an impressive 22 uniquely designed and charming rooms. From wooden beams to panelled walls and exquisite fireplaces, our hotel still houses many of the original features of the building

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Malmaison Oxford

Housed in a former prison, the rooms in our Oxford hotel are rather more spacious than your average jail cell and come complete with luxurious beds, super-fast Wi-Fi and power showers.

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Hampton by Hilton

Welcoming hotel near Oxford's historic centre and next to Kassam Stadium. Hampton by Hilton Oxford is situated conveniently close to both the business and leisure areas of Oxford. We are only 15 minutes from the historic centre and just an hour from Heathrow Airport. Oxford is the UK's oldest University City, where film fans explore the hallowed halls of Christ Church College, and punts glide gently along the River Cherwell. Our Oxford hotel is situated adjacent to Kassam Conference & Events Centre, home of Oxford Football Stadium and next door to the Ozone Leisure Park's multiplex cinema and choice of restaurants. We are within easy reach of Oxford Science Park and only a mile from the BMW mini plant, making our hotel a handy base for business travellers. Explore the pretty Cotswold villages and the rolling parkland of Blenheim Palace. Silverstone F1 racing circuit is 35 miles away and the famous Bicester village just 18 miles away. Our inviting, air-conditioned guest rooms offer contemporary amenities including Digital Check in, Hilton Honours Enrolment, free Wi - Fi, an ergonomic desk, a comfy bed and a 32- inch flat- screen TV. Refresh in the spacious bathroom, which features a walk-in power shower. Start you day right - there is a hot and cold buffet breakfast included when you stay at this Oxford hotel. Our 24-hour convenience hub stocks a selection of snacks, drinks and sundries. Exercise at a time that suits you in the 24- hour fitness centre. Relax with a drink in the lobby or grab a light bite in our casual snack area.

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Mercure Oxford Eastgate Hotel

The hotel has a central city location and is well known in the city.It is located on the south side of Oxford's High Street near to the Ruskin School of Drawing and Fine Art and the Examination Schools of Oxford University. The hotel is a converted 17th-century coaching inn located at the corner of Merton Street on the site of the town wall's former east gate. The building was converted by Edward Prioleau Warren in 1899–1900 and the stuccoed style of the building echoes other 18th century buildings in Oxford. Local history reports of the sound of men in armour and sightings of English Civil War era Royalist soldiers passing through walls to the hotel's location on the site of the old east gate and speculates about a surprise attack by Parliamentarian forces. The hotel is also where C. S. Lewis and J R R Tolkien would meet in the hotel as it was halfway between the two University colleges (Merton and Magdalen).

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